Review our pipeline for a detailed overview of our key initiatives and their status in the development and testing process.

#MVMD
Follows the science

Our mission is to solve some of the world’s leading health and wellness problems through novel innovations that improve the administration, efficacy and safety of new and existing medicines, therapies, and nutraceuticals.

Our patented technologies are embedded across critical projects that are focused on doing more with less, and making world-class drugs and vaccines more accessible.

Review our product pipeline below for a detailed overview of our key initiatives and related status.

Swipe to View Pipeline.

Program

Tech

Value Proposition

Macrocyclic Lactone Solubilization

Patented Quicksol™ technology for macrocyclic lactones, including Ivermectin and Selamectin, to enable enhanced injection or other liquid application of poorly soluble drugs to enhance bioavailability with new delivery options. 

Quicksol™

Development of Quicksol™, involves a patented process to improve solubility of traditionally insoluble molecules such as drugs in the macrocyclic lactone class.  With Quicksol™, we are able to form macrocyclic cyclodextrin inclusion complexes that when combined with a surfactant and dissolved in water, can form aqueous solutions.   The process includes the use of FDA approved non-ionic solvents to increase solubility and bioavailability of the molecule, opening possibilities for parenteral administration of drugs that have poor oral absorption

Formulation lab work on solubilization of Ivermectin
Completed
Solubilization and formulation work on Selamectin
Completed
Patent filing for macrocyclic lactone drugs.
Completed
GMP production of Soluvec™ and stability testing (formally Ivectosol™)
In Progress
Administration and bioavailability studies
In Progress

Husbandry Animals

Patented Quicksol™ technology for macrocyclic lactones, including Ivermectin and Selamectin, to enable enhanced injection or other liquid application of poorly soluble drugs to enhance bioavailability with new delivery options. 

Quicksol™

Challenges with livestock infections and administration of medication to cure animal infectious disease has caused significant reductions in yield across a variety of animal species, leading to pressure on agriculture economics, livestock management, and the overall production of food for the globally growing human population. We have applied our patented solubility technology to the drug Ivermectin and have developed the only form in the world that uses excipients that are currently approved by the US Food and Drug Administration, making it a leading candidate for broad husbandry animal treatments.

Formulation work on solubilization of ivermectin for husbandry application
Completed
Husbandry clinical trials - 1st stage
Completed
Husbandry clinical trials - 2nd stage
In Progress
Farm fishing trial program
In Progress
Commercialization in Bangladesh
In Progress

Cold Chain

Patented Quicksome™ liposome technology utilizes an advanced 2-step encapsulation and desiccation process to formulate normally highly un-bioavailable active ingredients into highly effective rapid oral dissolving product formats.

Quicksome™

Cold chain is a temperature-controlled supply chain that prescribes necessary conditions during the transport, storage, and handling of vaccines and drugs administered. With Quicksome™ technology we are working to enable vaccine distribution outside of cold chain, which will potentially support the use of less vaccine per dose, cost reduction, increase vaccine output, and be key for global disease eradication.

Formulation Lab Work
Completed
FDA confirmation of stabilization and preservation of Polio D Antigen via Quicksome™
Completed
Initial stabilization and preservation of Polio D Antigen
Completed
Preliminary cold chain testing with ELISA validation from 25- 40 degrees celsius

Based on the cold chain technology achievements announced in July of 2021, the Company has commenced additional characterization studies with its proprietary Quicksome™ technology to optimize application in the current Trivalent Inactivated Poliovirus Vaccine (tIPV) work and additional vaccines and proteins. The Company believes the technology would allow for long term stability and ease of global distribution, appropriate for pandemic preparedness, and other administration and distribution advantages, including potential sublingual applications that would eliminate the use of needles where desired.

Preliminary cold chain testing with ELISA validation from 25- 40 degrees celsius
Completed
FDA collaborative research agreement
Completed
Technology Characterization studies
In Progress
Quicksome vaccine application exploration analysis
In Progress
Targeted cold chain testing for vaccine applications
Planning

Oncology

Patented Quicksol™ technology for macrocyclic lactones, including Ivermectin and Selamectin, to enable enhanced injection or other liquid application of poorly soluble drugs to enhance bioavailability with new delivery options. 

Quicksol™

In oncology our work is currently focussed on applying our our Quicksol™ technology to reformulate existing molecules with anti-cancer effects as potential oncology treatments. Published literature has shown very interesting in vitro results for the potential effect of the macrocyclic lactone class on a wide variety of tumor types. Applying our technology to this class, and to other insoluble molecules, allows the investigation of these potential anti-cancer therapies as new options for oncology treatment. 

Patent filing for cancer adjuvant
Completed
Pre-clinical murine cell study - TNBC
Completed
Pre-clinical murine cell study - Malignant Melanoma
Completed
Pre-clinical murine cell study - NSCLC
Completed
Pre-clinical human cell lines proliferation and cell viability assays across expanded cancer types
In Progress
Pre-clinical human cell line derived xenograph models
Planning
Assessment of additional Quicksol™ formulation opportunities with other molecules
Planning

Sublingual Applications

Patented Quicksome™ liposome technology utilizes an advanced 2-step encapsulation and desiccation process to formulate normally highly un-bioavailable active ingredients into highly effective rapid oral dissolving product formats.

Quicksome™

Production of a stable, quick onset,  oral dissolve formulation to provide potential benefits of precise dosing, reduced variability, and dose sparing.

NUTRACEUTICALS
Formulation work on rapid dissolve formulations
Completed
Prototype formulations across different indications Weight loss, Energy, Pre-workout, Recovery, Sleep, Focus, Libido, Smokeless Nicotine and a variety of natural mushroom molecules.
Completed
Quicksome™ Cannabinoids Partner Licensing Contracting

Red White & Bloom is a publicly traded multi-state cannabis operator and house of premium brands that are available across the cannabis market in the United States. MVMD’s agreement with RWB establishes the terms upon which the Company will develop and license formulas using the Company’s Quicksome™ technology and novel cannabinoid solubilization techniques to be applied by RWB to various cannabis product applications. The Agreement grants RWB an exclusive 5-year license in Florida, Michigan and California to manufacture and distribute its cannabis products in exchange for the payment of product fees and ongoing sales royalties.  MVMD has no immediate control of the final in-market product timing or production scale as that is the responsibility of RWB.  MVMD is working closely with RWB to apply proprietary formulations across a number of branded medical and recreational product lines. The MVMD Quicksome™ sublingual applications, include a proprietary THC-based sleep formulation created for RWB, which is planned to be the initial product that RWB will introduce in the medical sleep market in the United States.  The product packaging, approvals and go-to-market timing, including providing market updates, are the sole responsibility of RWB.

Quicksome™ Cannabinoids partner licensing contracting
Completed
Quicksome™ Partner Licensing Contracting

MVMD has been working closely with Circadian Wellness on proprietary formulations for mushroom-infused products that achieve an increase in overall molecule efficacy with the Company’s Quicksome™ desiccated liposome technology applied across a variety of rapid dissolve sublingual and dermal products. Circadian is finalizing its product plans and go-to-market strategy for a broad line of naturally derived mushroom products that MVMD has been advised will be distributed initially in North America and expanded globally in future phases.  The initial work includes mushroom infused sublingual sleep and energy products and a hemp-based mushroom pain management cream.  Although outside of MVMD’s control, it is anticipated that Circadian will be introducing its first consumer products for sale in the United States in the first half of 2022 under its EONS brand.

Quicksome™ Partner licensing contracting
Completed
Ongoing Quicksome™ partner licensing business development
In Progress
Cannabinoids
Formulation work on rapid dissolve oral application with THC, CBD
Completed
Quicksome™ partner licensing contracting
Completed

Dose Sparing Adjuvant

Dose Sparing Adjuvant

Patent-Pending Porous Aluminum Nanostructure Adjuvant has high surface area for vaccine-antigen binding to provide dose sparing advantages with long-term stability in aqueous media, and greater stability in harsh environments.

Adjuvant

The purpose of the Company’s PANA process is to produce stable nano-particulate adjuvant with the intention of overcoming certain limitations of traditional aluminum-based adjuvants. The potential to use less vaccine per dose with a dose sparing adjuvant could lead to a number of potential benefits including: cost reduction, increased vaccine output, facilitation of mucosal and herd immunity, long-term stability in aqueous media, applications across hundreds of vaccines, and a key to global disease eradication.

Initial formulation experiments
Completed
Quantification analysis including electron microscopy
Completed
Porous Aluminum Nano-Structured Adjuvant Patent filing
Completed
Preliminary dose sparing and mucosal immunity trial
Completed
Expanded vaccine dose sparing evaluation
Planning
Follow on dose sparing adjuvant mucosal immunity studies
Planning

Diabetes

Patented Quicksome™ liposome technology utilizes an advanced 2-step encapsulation and desiccation process to formulate normally highly un-bioavailable active ingredients into highly effective rapid oral dissolving product formats.

Quicksome™

Although there has been significant innovation in recent years in relation to diabetes, insulin remains a cornerstone of treatment and that there is an unmet need in the insulin space, resulting from challenges such as costs, the use of needles, hypoglycaemia, and fear of injection. The company is currently exploring the application of QuicksomeTM technology to the needle-less administration of insulin through formulation experiments, to optimize the potential delivery of rapid-acting human insulin in a sublingual format.

Stability and formulation experimentation
In Progress

Infectious Diseases

Patented Quicksol™ technology for macrocyclic lactones, including Ivermectin and Selamectin, to enable enhanced injection or other liquid application of poorly soluble drugs to enhance bioavailability with new delivery options. 

Quicksol™

Application of patented Quicksol™ technology to the macrocyclic class of drugs to assess anti-infective properties across a wide range of diseases.

PARASITIC INFECTIONS
Administration and bioavailability trials
In Progress
505(b)(2) pathway with the U.S. Food and Drug Administration (FDA)
In Progress
Viral Infections
BSL-4 COVID-19 clearance trial
Completed
COVID treatment clinical trial program
Planning
Other Infectious Diseases
Stability and formulation experimentation
In Progress
Tuberculosis clinical trial program assessment
Planning

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